Depression is such an important topic which is why Dr. Rhonda Patrick released a 13-page article on depression that not only covers the recent episode they released on how exercise may mitigate depressive symptoms but also much more.
Before we get into the article I wanted to point out here at Ocean Splash Wellness we provide every single one of those treatments! Although we don't sell psychedelics we do train people how to achieve a psychedelic mind state naturally.
We are having an open house on Sunday August 11th @1PM.
We look forward to seeing you.
This article on depression covers everything from etiology including traumatic experiences, chronic inflammation and stress, decreased neurogenesis in the brain, disrupted circadian rhythm, gut microbiome dysbiosis, genetic predisposition and more. It also covers some emerging treatments including pharmacologic, exercise, diet, sauna use, omega-3 fatty acids, probiotics, light therapy, meditation, psychedelics, and transcranial direct stimulation.
One particularly interesting point covered in the depression topic page is the role that neurogenesis (the growth of new neurons) plays in both the etiology and treatment of depression. Disrupted neurogenesis and subsequent connectivity losses or failures have been implicated in depression. This leads to a decrease in neuroplasticity, which is the brain's ability to reorganize and remodel itself based on experiences, behaviors, and genes by forming new neural connections throughout life. Neuroplasticity is disrupted in depression and other mental health disorders and this has been shown to play a significant role in the onset and development of depression.
One of the most powerful growth factors produced in the brain called brain-derived growth factor (BDNF) has been shown to play a major role in increasing both neurogenesis and neuroplasticity. Reductions in plasma and serum levels of BDNF have been found in people with depression. Stress and other factors can reduce BDNF, whereas exercise consistently increases serum BDNF, which can cross the blood-brain barrier and have beneficial effects in the brain. For example, moderate to intense aerobic exercise for 40 minutes caused an average ~ 32% increase in serum BDNF levels compared to baseline levels.
This depression article dives deep into many different aspects of depression so make sure to check it out on the topics page on my website foundmyfitness.com!
In this short episode, Dr. Patrick discusses some of the compelling science including observational studies, randomized controlled trials, and human mechanistic studies that suggests exercise is a powerful tool for preventing or managing the symptoms of depression and mental illness. Moreover, she talks about the specific types of exercise and exercise parameters that evidence suggests might be the most helpful for depression.
▶︎ Get the episode's show notes
▶︎ View the new massively in-depth
FoundMyFitness depression topic page
▶︎ See the full interview with Dr. Charles Raison
▶︎ Get a copy of Dr. Charles Raison's book "The New Mind-Body Science of Depression"
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DISCLAIMER: This video is not meant to be a substitute for expert diagnosis or treatment of clinical conditions.